Pedro Antonio Del Carpio Ramos, Sergio Rafael Bernardo Del Carpio Hernández


El empleo de antibióticos promotores del crecimiento (APC) es, cada vez, menos sostenible en la alimentación de los cerdos comerciales destinados a la producción intensiva de carne, por lo que se está ensayando con alternativas dentro de las que se incluyen a los extractos de plantas (EP) con acción fitobiótica, como el tomillo (Thymusvulgaris) y el algarrobo europeo (Ceratonia siliqua). Se realizó el ensayo con 60 cerdos destetados con peso entre los 6 y 7 kilos, PIG x Camborough, hasta que concluyó la fase de Crecimiento I (33 días experimentales), con los siguientes tratamientos experimentales: T1, testigo; T2, 0.1 y T3, 0.2% de un producto comercial de extractos de tomillo y algarrobo europeo y se evaluó el efecto sobre el consumo de alimento, peso vivo, conversión alimenticia y mérito económico. Los resultados mostraron un efecto de ligera disminución del consumo de alimento, sin diferencias significativas entre tratamientos para el incremento de peso, ligera mayor eficiencia en la utilización del alimento para incrementar peso vivo en el Pre-Inicio e Inicio con 0.1% del producto, el mérito económico mostró la misma tendencia que la conversión alimenticia. Debido al, prácticamente, igual rendimiento se hace recomendable el empleo de 0.1% del producto en lugar de APC, disminuyendo de esta manera la posibilidad de antibiótico resistencia y probables mejoras en diferentes ítems de calidad de la carne.

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Abed, L. F. (2007). Antimicrobial activity of essential oils of some medicinal plants from Saudi Arabia. Saudi J. Biol. Sci. 14:53-60.

Aeschbach, R., Öliger, J. L., y Scott, B. C. (1994). Antioxidant actions of thymol, carvacrol, 6-gingerol, zingerone and hydroxytyrosol. Food and Chemical Toxicology, 32 (1): 31–36.

Aggarwal, B. B., y Shishodia, S. (2004). Suppresion of nuclear factor-kappa B activation pathway by spice-derived phytochemicals: reasoning for seasoning. Ann. N. Y. Acad. Sci. 1030:434-441.

Allan, P., y Bilei, G. (2005). Oregano improves reproductive performance of sows. Theriogenology. 63:716-721.

Ariza-Nieto, C., Bandrick, M., Baidoo, S. K., Anil, L., Molitor, T. W., y Hathaway, M. R. (2011). Effect of dietary supplementation of oregano essential oils to sows on colostrum and milk composition, growth pattern and immune status of suckling pigs. J. Anim. Sci. 89:1079- 1089.

Bakkali, F., Averbeck, S., Averbeck, D., y Idaomar, M. (2008). Biological effects of essential oils – A review. Food Chem. Toxicol. 46:446-475.

Baydar, H., Sağdiç, O., Özkan, G., y Karadoğan, T. (2004). Antibacterial activity and composition of essential oils from Origanum, Thymbra and Satureja species with commercial importance in Turkey. Food Control. 15:169-172.

Bishop, C. D. (1995). Anti-viral activity of the essential oil of Melaleuca alternifolia. J. Essential Oil Res. 7:641-644.

Botsoglou, N. A., Florou-Paner, P., Christaki, E., Fletouris, D. J., y Spais, A. B. (2002). Effect of dietary oregano essential oil on performance of chickens and on iron-induced lipid oxidation of breast, thigh and abdominal fat tissues. Br. Poult. Sci. 43:223-230.

Braga, P. C., Dal Sasso, M., Culici, M., Bianchi, T., Bordoni, L., y Marabini, L. (2006). Anti-inflammatory activity of thymol: inhibitory effect on the release of human neutrophil elastase. Pharmacology, 77 (3): 130–136.

Burt, S. (2004). Essential oils: their antibacterial properties and potential applications in foods-a review. Int. J. Food Microbiol. 94:223-253.

Calsamiglia, S., Busquet, M., Cardozo, P. W., Castillejos, L., y Ferret, A. (2007). Invited review: essential oils as modifers of rumen microbial fermentation. J. Dairy Sci. 90:2580-2595.

Cullen, S. P., Monahan, F. J., Callan, J. J., y O’Doherty, J. V. (2005). The effect of dietary garlic and rosemary on grower-finisher pig performance and sensory characteristics of porl. Irish J. Agr. Food Res. 44:57-67.

Dinarello, C. A. (2000). Proinflammatory cytokines. Chest. 118:503-508.

Dorman, H. J. D. y Deans, S. G. (2000). Antimicrobial agents from plants: antibacterial activity of plant volatile oils. J.Appl. Microbiol. 88:308-316.

Duke, J. A. (1986). CRC handbook of medicinal herbs. CRC press, Florida.

Dundar, E., Olgun, E. G., Isiksoy, S., Kurkcuoglu, M., Baser, K. H. C., y Bal, C. (2008). The effects of intra-rectal and intra-peritoneal application of Origanum onites L. essential oil on 2, 4, 6-trinitrobenzenesulfolic acid-induced colitis in the rat. Exp. Toxical. Pathol. 59:399-408.

Dung, N. T., Bajpai, V. K., Yoon, J. I., y Kang, S. C. (2009). Anti-inflammatory effects of essential oil isolated from the buds of Cleistocalyx operculatus (Roxb.) Merr and Perry. Food Chem. Toxicol. 47:449-453.

Dunshea, F. R., Suster, D., Kerton, D. J., y Leury, B. J. (2003). A capsacin analogue improves growth and dressing rate in pigs, particularly gilts. In J. E. Paterson (Ed.). Manipulating pig production (Vol. IX, pp. 26). Werribee, Australia: Australasian Pig Science Association Inc.

Economou, K. D., Oreopoulou, V., y Thomopoulos, C. D. (1991). Antioxidant activity of some plant extracts of the family Labiatae. J. Am. Oil Chem. Soc. 66:792-799.

Essawi, T. y Srour, M. (2000). Screening of some Palestinian medicinal plants for antibacterial activity. Journal of Ethnopharmacology, 70 (3): 343–349.

Frankič, T., Levart, A., y Salobir, J. (2010). The effect of vitamin E and plant extract mixture composed of carvacrol, cinnamaldehyde and capsaicin on oxidative stress induced by high PUFA load in young pigs. Animal. 4:572-578.

Garozzo, A., Timpanaro, R., Bisignano, B., Furneri, P. M., Bisignano, G., y Castro, A. (2009). In vitro antiviral activity of Melaleuca alternifolia essential oil. Lett. Appl. Microbiol. 49:806-808.

Grela, E. R., Krusiński, R., y Matras, J. (1998). Efficacy of diets with antibiotic and herb mixture additives in feeding of growing-finishing pigs. J. Anim. Feed Sci. 7:171-175.

Gülçin, Ì., Şat, İ. G., Beydemir, Ş., Elmastaş, M., y Küfrevioğlu, Ö. I. (2004). Comparison of antioxidant activity of clove (Eugenia caryophylata Thunb) buds and lavender (Lavandula stoechas L.). Food Chem. 87:393-400.

Hammer, K. A., Carson, C. F., y Riley, T. V. (1999). Antimicrobial activity of essential oils and other plant extracts. J. Appl. Microbiol. 86:985-990.

Hart, P. H., Brand, C., Carson, C. F., Riley, T. V., Prager, R. H., y Finlay-Jones, J. J. (2000). Terpinen-4-olm the main component of the essential oil of Melaleuca alternifolia (tea tree oil), suppresses inflammatory mediator production by activated human monocytes. Inflamm. Res. 49:619-626.

Herrmann, K. M. y Weaver, L. M. (1999). The shikimate pathway. Annu. Rev. Plant Physiol. Plant Mol. Biol. 50: 473-503.

Hudaib, M., Speroni, E., Di Pietra, A. M., y Cavrini, V. (2002). GC/MS evaluation of thyme (Thymus vulgaris L.) oil composition and variations during the vegetative cycle. Journal of Pharmaceutical and Biomedical Analysis, 29 (4): 691–700.

Ilsley, S., Miller, H., Greathead, H., y Kamel, C. (2002). Herbal sow diets boost preweaning growth. Feed Mix. 10:24-25.

Jacela, J. Y., DeRouchey, J. M., Tokach, M. D, Goodband, R. D, Nelssen, J. L., Renter, D. G., y Dritz, S. S. (2010). Feed additives for swine: Fact sheets-flavors and mold inhibitors, mycotoxin binders, and antioxidants. Journal of Swine Health and Production, 18(1): 27-32.

Janz, J. A. M., Morel, P. C. H., Wilkinson, B. H. P., y Purchas, R. W. (2007). Preliminary investigation of the effects of low-level dietary inclusion of fragrant essential oils and oleoresins on pig performance and pork quality. Meat Sci. 75:350-355.

Kerrola, K. (1995). Literature review: Isolation of essential oils and flavor compounds by dense carbon dioxide. Food Rev. Int., 11:547-573.

Kim, S. S., Oh, O., Min H., Park, E., Kim, Y., Park, H. J.,…Lee, S. K. (2003). Eugenol suppresses cyclooxygenase-2 expression in lipopolysaccharide-stimulated mouse macrophage RAW264.7 cells. Life Sci. 73:337-348.

Kotrotsios, N. V., Christaki, E., Bonos, E., y Floru-Paneri, P. (2012). Dietary carob pods on growth performance and meat quality of fattening pigs. Asian Australian Journal Animal Science, 6: 880-885.

Landa, P., Kokoska, L., Pribylova, M., Vanek, T., y Marsik, P. (2009). In vitro anti-inflammatory activity of carvacrol: inhibitory effect on COX-2 catalyzed prostaglandin E2 biosynthesis. Arch. Pharm. Res. 32:75-78.

Lang, A., Lahav, M., Sakhnini, E., Barshack, I., Fidder, H. H., Avidan, B., Bardan, E., Hershkoviz, R., Bar-Meir, S., y Chowers, Y. (2004). Allicin inhibits spontaneous and TNF-α induced secretion of proinfammatory cytokines and chemokines from intestinal epithelial cells. Clin. Nutr. 23:1199-1208.

Lawrence, B. M. y Reynolds, R. J. (1984). Progress in essential oils. Perfumer and Flavorist. 9:23-31.

Lee, K. -W., H. Events, and A. C. Beynen. 2004. Essential oils in broiler nutrition. Int. J. Poult. Sci. 3:738-752.

Lee, S. H., Lee, S. Y., Son, D. J., Lee, H., Yoo, H. S., Song, S., Oh, K. W., Han, D. C., B. M. K, y Hong, J. T. (2005). Inhibitory effect of 2’-hydroxycinnamaldehyde on nitric oxide production through inhibition of NF-κB activation in RAW 264.7 cells. Biochem. Pharmacol. 69:791-799.

Lee, Y., Hung, S., Pai, S., Lee, Y., and Yang, S. (2007). Eugenol suppressed and expression of lipopolysaccharide-induced proinfammatory mediators in human macrophages. J. Endod. 33:698-702.

Lens-Lisbonne, C., Cremieux, A., Maillard, C., and Balansard, G. (1987). Methods for evaluation of antibacterial activity of essential oils: application to essences of thyme and cinnamon. J. Pharm. Belg. 42:297-302.

Li, W., Tsubouchi, R., Qiao, S., Haneda, M, Murakami, K, and Yoshino, M. (2006). Inhibitory action of eugenol compounds on the production of nitric oxide in RAW264.7 macrophages. Biomed. Res. 27:69-74.

MacMicking, J., Xie, Q., y Nathan, C. (1997). Nitric oxide and macrophage function. Annu. Rev. Immunol. 15:323-350.

Miura, K., Kikuzaki, H., y Nakatani, N. (2002). Antioxidant activity of chemical components from sage (Salvia officinalis L.) and thyme (Thymus vulgaris L.) measured by the oil stability index method. Journal of Agricultural and Food Chemistry, 50 (7): 1845–1851.

Miziorko, H. M. (2011). Enzymes of the mevalonate pathway of isoprenoid biosynthesis. Arch. Biochem. Biophys. 505:131-143.

Moon, T., Wilkinson, J. M., y Cavanagh, H. M. A. (2006). Antiparasitic activity of two Lavandula essential oils against Giardia duodenalis, Trichomonas vaginalis and Hexamita inflata. Parasitol. Res. 99:722-728.

Oboh, G., Puntel, R. L., y Rocha, J. B. T. (2007). Hot pepper (Capsicum annuum, Tepin and Capsicum chinese, Habanero) prevent Fe2+-induced lipid peroxidation in brain – in vitro. Food Chem. 102:178-185.

Ostle, B. (1979). Estadística Aplicada. Editorial LIMUSA. México, D. F.

Pandey, R., Kalra, A., Tandon, S., Methrotra, N., Singh, H. N., y Kumar, S. (2000). Essential oils as potent sources of nematicidal compounds. J. Phytopathology. 148:501-502.

Pessoa, L. M., Morais, S. M., Bevilaqua, C. M. L., y Luciano, J. H. S. (2002). Anthelmintic activity of essential oil of Ocimum gratissimum Linn. and eugenol against Haemonchus contortus. Vet. Parasitol. 109:59-63.

Pettigrew, J. E. (2006). Reduced use of antibiotic growth promoters in diets fed to weanling pigs: dietary tools, part 1. Anim. Biotechnol. 17:207-215.

Pinto. E., Pina-Vaz, C., Salgueiro, L., Gonçalves, M. J., Costa-de-Oliveira, S., Cavaleiro, C., Palmeira, A., Rodrigues, A., y Martinez-de-Oliveira, J. (2006). Antifungal activity of the essential oil of Thymus pulegioides on Candida, Aspergillu and dermatophyte species. J. Med. Microbiol. 55:1367-1373.

Scheffler, E. (1982). Bioestadística. Fondo Educativo Interamericano. EE. UU. de N. A.

Seigler, D. S. (1998). Phenylpropanoids. In: Plant secondary metabolism. D. S. Seigler. Ed. Kluwer Academic Publishers, Boston. pp. 106-129.

Simonson, R. R. (2004). Antimicrobial properties of herbs and spices and their potential use in diets for pigs. Newport Laboratories, Inc. submitted to CRIS.

Slamenova, D., Horvathova, E., Marsalkova, L., y Wsolova, L. (2008). Carvacrol given to rats in drinking water reduces the level of DNA lesions induced in freshly isolated hepatocytes and testicular cells by H2O2. Neoplasma. 55:394-399.

Sökmen, M., Serkedjieva, J., Daferera, D., Gulluce, M., Polissiou, M., Tepe, B., Akpulat, H. A., Sahin, F, y Sokmen, A. (2004). In vitro antioxidant, antimicrobial, and antiviral activities of the essential oil and various extracts from herbal parts and callus cultures of Origanum acutidens. J. Agric. Food Chem. 52:3309-3312.

Soliman, K. M. y Badeaa, R. I. (2002). Effect of oil extracted from some medicinal plants on different mycotoxigenic fungi. Food and Chemical Toxicology, 40 (11): 1669–1675.

Sosa, S., Altinier, G., Politi, M., Braca, A., Morelli, I., y Loggia, R. D. (2005). Extracts and constituents of Lavandula multifida with topical anti-inflammatory activity. Phytomedicine. 12:271-277.

Stein, H. H. y Kil, D. Y. (2006). Reduced use of antibiotic growth promoters in diets fed to weanling piglets: dietary tools, part 2. Anim. Biotech. 17:217-231.

Sulabo R. C., Jacela J. Y., DeRouchey J. M., Tokach M. D., Neher F., Goodband R. D., Dritz, S. S. and Nelssen J. L. (2007). Ef- fects of phytobiotics (BIOMIN® P.E.P.) on nursery pig performance. Kansas Agric. Exp. Sta. Prog. Rep. 985, 94-98.

Surburg, H. y Panten, J. (2006). Common fragrance and flavor materials: preparation, properties and uses. Wiley-VCH, Weinheim, p 289-303.

Suzuki, Y. y Furuta, H. (1988). Stimulation of guinea pig neutrophil superoxide anion-producing system with thymol. Inflammation, 12 (6): 575–584.

Tabasum, S., Mun, H-S., Manirul, Md., Ko, S-Y., y Yang, C-J. (2016). Effects of dietary natural and fermented herb combination on growth performance, carcass traits and meat quality in grower-finisher pigs. Meat Science, 122: 7–15.

Tung, Y., Chua, M., Wang, S., y Chang, S. (2008). Anti-inflammation activities of essential oil and its constituents from indigenous cinnamon (Cinnamomum osmophloeum) twigs. Bioresource Technol. 99:3908-3913.

Ultee, A. y Smid, E. J. (2001). Influence of carvacrol on growth and toxin production by Bacillus cereus. Int. J. Food Microbiol. 64:373-383.

Venturini, M. E., Blanco, D., y Oria, R. (2002). In vitro antifungal activity of several antimicrobial compounds against Penicillium expansum. Journal of Food Protection, 65 (5): 834–839.

Walter, B. M. y Bilkei, G. (2004). Immunostimulatory effect of dietary oregano etheric oils on lymphocytes from growth-retarded, low-weight growing-finishing pigs and productivity. Tijdschrift voor Diergeneeskunde. 129:178-181.

Wilson, D. J., Patton, S., Florova, G., Hale, V., y Reynolds, K. A. (1998). The shikimic acid pathway and polyketide biosynthesis. J. In. Microbiol. Biotech. 20:299-303.

Wong, S. Y. Y., Grant, I. R., Friedman, M., Elliott, C. T., y Situ, C. (2008). Antibacterial activities of naturally occurring compounds against Mycobacterium avium subsp. paratuberculosis. Appl. Env. Microbiol. 74:5986-5990.

Zou, Y., Xiang, Q., Wang, J., Wei, H., y Peng, J. (2016). Effects of oregano essential oil or quercetin supplementation on body weight loss, carcass characteristics, meat quality and antioxidant status in finishing pigs under transport stress. Livestock Science, 192: 33–38.

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